Structural and Systemic Neurobiology

(AG Lidia Bakota)

Bakota L, and Brandt R (2023) Why kiss-and-hop explains that tau does not stabilize microtubules and does not interfere with axonal transport (at physiological conditions). Cytoskeleton (online ahead of print)

Rierola M, Trushina NI, Holtmannspotter M, Kurre R, and Bakota L (2023) Lattice light-sheet microscopy and evaluation of dendritic transport in cultured hippocampal tissue reveal high variability in mobility of the KIF1A motor domain and entry into dendritic spines. Brain Res. Bull. 194:13-22

Hrynchak MV, Rierola M, Golovyashkina N, Penazzi L, Pump WC, David B, Sündermann F, Brandt, and Bakota L (2020) Chronic Presence of Oligomeric Aβ Differentially Modulates Spine Parameters in the Hippocampus and Cortex of Mice With Low APP Transgene Expression. Front. Synaptic Neurosci. 12:16

Brandt R, Trushina NI, and Bakota L (2020) Much more than a cytoskeletal protein: Physiological and pathological functions of the non-microtubule binding region of tau. Front. Neurol. 11:590059

Brandt R, and Bakota L (2017) Microtubule dynamics and the neurodegenerative triad of Alzheimer's disease: The hidden connection. J. Neurochem. 143:409-417

Bakota L, Ussif A, Jeserich G, and Brandt R (2017) Systemic and network functions of the microtubule-associated protein tau: Implications for tau-based therapies. Mol. Cell. Neuroscience 84:132-141

Penazzi L, Lorengel J, Sündermann F, Golovyashkina N, Marre S, Mathis CMB, Lewejohann L, Brandt R, and Bakota L (2017) DMSO modulates CNS function in a preclinical Alzheimer's disease model. Neuropharmacology 113:434-444

Bakota L, and Brandt R (2016) Tau Biology and Tau-Directed Therapies for Alzheimer's Disease. Drugs 76:301-313

Golovyashkina N, Sündermann F, Brandt R, and Bakota L (2014) Reconstruction and morphometric analysis of hippocampal neurons from mice expressing fluorescent proteins. NeuroMethods 87:251-262

Bakota L, Brandt R, and Heinisch JJ (2012) Triple mammalian/yeast/bacterial shuttle vectors for single and combined Lentivirus- and Sindbis virus-mediated infections of neurons. Mol. Genet. Genomics 287:313-324

Sündermann F, Golovyashkina N, Tackenberg C, Brandt R, and Bakota L (2012) High-resolution imaging and evaluation of spines in organotypic hippocampal slice cultures. Methods Mol. Biol. 846:277-293

Bakota L, and Brandt R (2009) Live cell imaging in the study of neurodegeneration. Int. Rev. Cell Mol. Biol. 276:49-103

Bakota L, Szikra J, Toth G, and Gulya K (1998) Slide-binding characterization and autoradiographic localization of delta opioid receptors in rat and mouse brains with the tetrapeptide antagonist (3H)TIPP. Life Sci. 63:1377-1385

Bakota L, and Brandt R (eds.) Confocal and multiphoton laser-scanning microscopy of neuronal tissue: Applications and quantitative image analysis. New York: Humana Press, 2014.

Tulva, Kerli (2024) The role of tau in neuronal cytoskeleton organization and inflammation. Fachbereich Biologie/Chemie, Universität Osnabrück.
Abreu, Nanci Daniela Monteiro (2024) The Role of Tau in Hippocampal CA1 Neurons - An Electrophysiological Approach. Fachbereich Biologie/Chemie, Universität Osnabrück.
Rierola, Marina (2022) Distinct modulation of neuronal domains by Abeta, tau, and α-synuclein affects dendritic connectivity in hippocampal pyramidal neurons. Fachbereich Biologie/Chemie, Universität Osnabrück.
Hrynchak, Mariya (2021) Functional synergy of Abeta oligomers and human tau protein in mice and ex vivo cultures. Fachbereich Biologie/Chemie, Universität Osnabrück.
Ussif, Abdala Mumuni (2019) Effects of MAPtau knockout on electrophysiological, biochemical and dendritic morphometric parameters. Fachbereich Biologie/Chemie, Universität Osnabrück.
Penazzi, Lorène (2016) Pharmacological intervention to reverse structural and functional changes in neurons chronically exposed to moderate Aß levels. Fachbereich Biologie/Chemie, Universität Osnabrück.